Adrenaline Nasal Spray for Treatment of Anaphylaxis in Children

Cov lus qhia rau adrenaline nasal spray neffy tau nthuav dav (los ntawm US FDA) kom suav nrog cov menyuam yaus hnub nyoog plaub xyoos thiab laus dua uas hnyav 15 txog 30 kg.  

Ua ntej 9 Lub Yim Hli 2025, neffy tau txais kev pom zoo rau kev kho mob xwm txheej ceev ntawm hom 1 kev tsis haum tshuaj, suav nrog cov uas ua rau muaj kev phom sij rau lub neej, hauv cov neeg laus thiab menyuam yaus uas hnyav 30 kg (66 phaus). Nws yog thawj FDA-pom zoo tshuaj tsuag qhov ntswg los kho anaphylaxis thiab thawj cov tshuaj epinephrine rau kev kho mob anaphylaxis uas tsis yog txhaj tshuaj. 

Tim 28 lub 2024 hli XNUMX, Eurneffy, thawj qhov ntswg adrenaline tshuaj tsuag rau kev kho mob xwm txheej ceev tiv thaiv kev tsis haum tshuaj (anaphylaxis) tau tso cai kev lag luam hauv European Union (EU) los ntawm European Medicine Agency (EMA).  

Cov tshuaj tsuag adrenaline rau kev kho mob xwm txheej ceev tiv thaiv kev tsis haum tshuaj (anaphylaxis) tab tom tos kev pom zoo hauv United Kingdon thiab Canada.  

Kev pom zoo ntawm adrenaline qhov ntswg tshuaj rau kev kho mob thaum muaj xwm txheej ceev tiv thaiv kev tsis haum tshuaj muab lwm txoj hauv kev ntawm kev tswj hwm ntawm adrenaline rau cov neeg (tshwj xeeb tshaj yog cov menyuam yaus) tsis txaus siab rau kev txhaj tshuaj thiab ntsib teeb meem kev phom sij txog lub neej ntawm anaphylaxis.   

Adrenaline (tseem hu ua epinephrine) yog tib txoj kev cawm txoj sia rau anaphylaxis. Nws muaj nyob rau tam sim no tsuas yog kev txhaj tshuaj feem ntau yog siv los ntawm kev txhaj tshuaj intramuscular (IM) lossis txoj hauv kev (IV) txoj hauv kev. Neffy/Eurnefy yog thawj cov khoom lag luam epinephrine rau kev kho mob anaphylaxis uas tsis yog siv los ntawm kev txhaj tshuaj. Nws yog ib koob tshuaj tsuag qhov ntswg rau hauv ib lub qhov ntswg. Ib koob thib ob (siv tshuaj tsuag qhov ntswg tshiab rau tib lub qhov ntswg) yuav muab tau yog tias tsis muaj kev txhim kho ntawm cov tsos mob lossis cov tsos mob hnyav dua. Cov neeg mob yuav tau nrhiav kev pab kho mob xwm txheej ceev rau kev saib xyuas ze.   

Anaphylaxis yog suav tias yog kev kho mob xwm txheej ceev. Nws yog ib qho mob hnyav, ua rau muaj kev phom sij rau lub neej uas feem ntau cuam tshuam nrog ntau qhov chaw ntawm lub cev. Qee cov zaub mov, tshuaj thiab kab tsuag yog cov tshuaj ua xua uas tuaj yeem ua rau anaphylaxis. Cov tsos mob feem ntau tshwm sim nyob rau hauv feeb tom qab kis tau thiab suav nrog, tab sis tsis txwv rau, khaus, o, khaus, ntuav, ua pa nyuaj thiab tsis nco qab.   

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References:  

1. FDA Xov Xwm Tshaj Tawm -FDA Roundup: 7 Lub Peb Hlis 2025. Muaj nyob ntawm https://www.fda.gov/news-events/press-announcements/fda-roundup-march-7-2025  

2. EMA. Xov Xwm - Thawj qhov ntswg adrenaline tshuaj rau kev kho mob xwm txheej ceev tiv thaiv kev tsis haum tshuaj. Tshaj tawm 28 Lub Rau Hli 2024. Muaj nyob ntawm https://www.ema.europa.eu/en/news/first-nasal-adrenaline-spray-emergency-treatment-against-allergic-reactions  

3. ARS Pharmaceuticals Cov Ntaub Ntawv rau Kev Pom Zoo ntawm neffy® hauv Canada thiab United Kingdom sawv cev ntawm Daim Ntawv Tso Cai Tus Tswv Cuab ALK-Abelló A/S. Tshaj tawm 6 Lub Ib Hlis 2025. Muaj nyob ntawm https://ir.ars-pharma.com/news-releases/news-release-details/ars-pharmaceuticals-files-approval-neffyr-canada-and-united  

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Tshooj cai  

• Epinephrine (los yog Adrenaline) Nasal Spray for Treatment of Anaphylaxis (10 Lub Yim Hli 2024)  

• Kev Kho Mob Yooj Yim Tshiab rau Peanut Allergy (Lub Kaum Ib Hlis 15, 2018) 

• Tricking Lub Cev: Txoj Kev Tiv Thaiv Tshiab los Tackle Allergies (Lub Plaub Hlis 15, 2018) 

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