Ib txoj kev tshawb fawb tsis ntev los no tau kwv yees tus kab mob ntau zaus ntawm tus kab mob herpes simplex virus (HSV) thiab kab mob ntawm qhov chaw mos (GUD). Cov kev kwv yees qhia tau hais tias kwv yees li 846 lab tus tib neeg hnub nyoog 15-49 xyoo tau nyob nrog cov kab mob herpes ntawm qhov chaw mos xyoo 2020, uas yog ntau dua 20% ntawm cov neeg hauv pawg hnub nyoog no thoob ntiaj teb. Rau kev sib piv, tag nrho cov neeg muaj tus kab mob herpes qhov chaw mos hauv xyoo 2016 yog kwv yees li ib nrab billion. Cov kev mob tshwm sim ntau thiab ntau thiab kev loj hlob txhua xyoo hauv xyoo tas los no hu rau kev tiv thaiv zoo dua. Tam sim no, tsis muaj cov tshuaj tiv thaiv HSV muaj ntawv tso cai. Muaj ntau tus neeg sib tw tshuaj tiv thaiv HSV hauv cov raj xa dej tab sis txhua tus nyob hauv lub xeev preclinical, tseem tsis tau nkag mus rau theem 1 ntawm tib neeg kev sim tshuaj.
Tus kab mob Herpes simplex (HSV) yog ib hom kab mob DNA uas muaj ob leeg nyob hauv tsev neeg herpesviridae. Nws khi rau tuav cov cellular receptors thiab rov ua dua nyob rau hauv ntau cov ntaub so ntswg xws li epithelial hlwb, neurons, thiab lwm yam. Nws ua rau cov kab mob uas yog asymptomatic feem ntau ntawm cov sij hawm tab sis tej zaum yuav ua rau mob hlwv los yog rwj. Tus kab mob kis tau los ntawm kev sib cuag ntawm daim tawv nqaij.
Tus kab mob HSV yog lub neej ntev, nws kho tau tab sis kho tsis tau.
HSV muaj ob hom. HSV-1 feem ntau ua rau qhov ncauj herpes thiab kis tau los ntawm kev sib cuag ntawm qhov ncauj, txawm li cas los xij nws tuaj yeem koom nrog hauv qhov chaw mos thiab kis mus rau kev sib deev.
HSV-2 ua rau qhov chaw mos herpes thiab kis tau los ntawm kev sib deev. Tus kab mob genital ulcer (GUD) yog txuam nrog HSV-2 thiab HSV-1.
Cov tib neeg cuam tshuam los ntawm tus kab mob HSV, tshwj xeeb tshaj yog HSV-2 muaj kev pheej hmoo siab dua ntawm kev kis tus kab mob tib neeg tiv thaiv kab mob (HIV).
Tus kab mob Herpes simplex tau paub tias tau cuam tshuam ntau tus neeg thoob ntiaj teb. Hauv xyoo 2016, kev tshawb fawb kwv yees li ntawm cov neeg no. Nws tau pom tias kwv yees li ib nrab lab tus tib neeg tau kis kab mob ntawm qhov chaw mos los ntawm HSV-2 thiab HSV-1 thaum ntau txhiab tus neeg tau cuam tshuam nrog qhov ncauj vim HSV-1. Tsis tas li ntawd, ntau lab tus neeg cuam tshuam tau muaj kev pheej hmoo kis tus kab mob human immunodeficiency virus (HIV).
Ib txoj kev tshawb fawb tsis ntev los no tau tshaj tawm rau 10 Lub Kaum Ob Hlis 2024 tau pom qhov teeb meem ntawm qhov teeb meem no. Siv cov qauv lej ntsuas thiab cov qauv nkag los ntawm kev tshuaj xyuas thiab ntsuas meta-kev soj ntsuam ntawm HSV cov ntaub ntawv nthuav dav rau txhua cheeb tsam WHO, txoj kev tshawb fawb tau tsim kev kwv yees ntawm qhov tshwm sim thiab qhov tshwm sim ntawm qhov chaw mos HSV kis thoob ntiaj teb xyoo 2020 hauv 15-49 xyoo pawg, Kab mob ntawm qhov chaw mos (GUD) tshwm sim los ntawm ob hom HSV thiab cov kab mob uas tsis yog qhov chaw mos los ntawm HSV-1.
Cov lus: Kab mob ntau zaus ntawm qhov chaw mos HSV kis tau rau xyoo 2020 hauv pawg hnub nyoog 15-49 xyoo.
| Tus naj npawb ntawm cov neeg laus 15-49 xyoos cuam tshuam los ntawm qhov chaw mos HSV kis thoob ntiaj teb nyob rau hauv xyoo 2020 |
| Genital HSV kab mob vim HSV-2: →25.6 lab tus neeg mob tshiab (qhov xwm txheej), →519.5 lab (los yog 13.3%) tag nrho cov teeb meem uas twb muaj lawm (prevalence) →187.9 lab nrog tsawg kawg ib ntu ntawm HSV-attributable Genital ulcer disease (GUD) rau HSV-2 |
| Kab mob HSV ntawm qhov chaw mos vim HSV-1: →16.8 lab tus neeg mob tshiab (qhov xwm txheej) →376.2 lab (los yog 10.2%) tag nrho cov teeb meem uas twb muaj lawm (prevalence) →16.7 lab nrog tsawg kawg ib ntu ntawm HSV-attributable Genital ulcer disease (GUD) rau HSV-2 |
| →846 lab yog tag nrho cov neeg muaj hnub nyoog 15-49 xyoo nyob nrog cov kab mob ntawm qhov chaw mos (prevalence of HSV-2 plus prevalence of HSV-1). Qhov no yog ntau tshaj 20% ntawm cov neeg hauv pawg hnub nyoog no thoob ntiaj teb. →204.6 lab yog tag nrho cov neeg muaj hnub nyoog 15-49 xyoo nrog tsawg kawg ib ntu ntawm HSV-attributable GUD →Kwv yees li 42 lab tus tib neeg kis tus kab mob herpes tshiab ntawm qhov chaw mos txhua xyoo. |
| (Qhov chaw: Harfouche M., thiab al 2024) |
Raws li kev tshawb fawb tsis ntev los no, tag nrho ntawm 846 lab tus tib neeg hnub nyoog 15-49 xyoo tau nyob nrog cov kab mob herpes ntawm qhov chaw mos (vim HSV-2 thiab HSV-1) hauv xyoo 2020. Rau kev sib piv, xyoo 2016, kwv yees li ib nrab lab tus tib neeg. (hauv txhua pab pawg hnub nyoog) muaj kab mob herpes ntawm qhov chaw mos.
Kom meej meej, kab mob HSV qhov chaw mos muaj qhov tshwm sim ntau heev thiab muaj feem ntau. Hauv xyoo 2020, ntau dua 20% ntawm cov neeg nyob hauv 15-49 xyoo pab pawg thoob ntiaj teb tau kis tus kab mob ntawm qhov chaw mos. Kev txhawj xeeb, cov lej tau nce nrawm nrawm hauv xyoo tas los no.
Qhov xwm txheej hu kom muaj kev tiv thaiv zoo dua thiab kev kho mob ntsuas. Tam sim no, tsis muaj cov tshuaj tiv thaiv HSV muaj ntawv tso cai. Muaj ntau tus neeg sib tw tshuaj tiv thaiv HSV hauv cov raj xa dej tab sis txhua tus nyob hauv lub xeev preclinical, tseem tsis tau nkag mus rau theem 1 ntawm tib neeg kev sim tshuaj.
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References:
- WHO. Daim ntawv tseeb - Herpes simplex virus. 10 Kaum Ob Hlis 2024. Muaj nyob ntawm https://www.who.int/news-room/fact-sheets/detail/herpes-simplex-virus
- James, Charlotte et al. "Tus kab mob Herpes simplex: kev kis kab mob thoob ntiaj teb thiab kev kwv yees, 2016." Cov ntawv xov xwm ntawm World Health Organization vol. 98,5 (2020): 315-329. Muaj nyob ntawm https://pmc.ncbi.nlm.nih.gov/articles/PMC7265941/
- Harfouche M., et al 2024. Kwv yees thoob ntiaj teb thiab cheeb tsam qhov xwm txheej thiab qhov tshwm sim ntawm tus kab mob herpes simplex kab mob thiab kab mob ntawm qhov chaw mos hauv xyoo 2020: kev tshuaj ntsuam xyuas lej. Kev sib deev kis kab mob, BMJ Journals. Published Online First: 10 Kaum Ob Hlis 2024. DOI: https://doi.org/10.1136/sextrans-2024-056307
- WHO xov xwm - Ntau tshaj 1 ntawm 5 tus neeg laus thoob ntiaj teb muaj tus kab mob herpes qhov chaw mos - WHO. Tshaj tawm 11 Kaum Ob Hlis 2024. Muaj nyob ntawm https://www.who.int/news/item/11-12-2024-over-1-in-5-adults-worldwide-has-a-genital-herpes-infection-who
- WHO. Kev txhaj tshuaj, tshuaj tiv thaiv thiab tshuaj lom neeg - Herpes Simplex Virus. Muaj nyob ntawm https://www.who.int/teams/immunization-vaccines-and-biologicals/diseases/herpes-simplex-virus
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