Monkeypox (Mpox) Vaccines: LEEJ TWG pib txheej txheem EUL  

Raws li qhov tshwm sim loj thiab loj hlob ntawm tus kab mob liab (Mpox) nyob rau hauv Democratic Republic of the Congo (DRC) uas tam sim no tau nthuav tawm sab nraud lub tebchaws thiab nrhiav pom tus kab mob tshiab uas tshwm sim thawj zaug thaum lub Cuaj Hlis 2023 sab nraum DRC, WHO tau caw cov tuam txhab tsim khoom. mpox cov tshuaj tiv thaiv kom xa Daim Ntawv Qhia Txog Kev Txaus Siab rau Kev Siv Thaum Muaj Xwm Ceev (EUL) suav nrog cov ntaub ntawv los ua pov thawj tias cov tshuaj tiv thaiv muaj kev nyab xeeb, muaj txiaj ntsig, muaj txiaj ntsig zoo thiab tsim nyog rau cov hom phiaj pej xeem. 

Cov txheej txheem EUL yog txheej txheem kev tso cai siv thaum muaj xwm txheej ceev, tshwj xeeb tsim los txhawm rau kom muaj cov khoom kho mob tsis muaj ntawv tso cai zoo li cov tshuaj tiv thaiv uas xav tau hauv cov xwm txheej xwm txheej ceev rau pej xeem kev noj qab haus huv. Kev pom zoo ntawm EUL yuav txhim kho qhov muaj tshuaj tiv thaiv tshwj xeeb rau cov chaw muaj kev txwv tsis pub muaj teeb meem uas tseem tsis tau tshaj tawm lawv tus kheej kev pom zoo hauv lub tebchaws. EUL tseem tso cai rau cov koom tes suav nrog Gavi thiab UNICEF txhawm rau muab cov tshuaj tiv thaiv rau kev faib khoom. 

Monkeypox virus (MPXV) yog ob-kab DNA kab mob uas muaj nyob rau hauv genus Orthopoxvirus nrog rau cov tshuaj tiv thaiv kab mob (VACV) thiab variola virus (VARV). Nws muaj feem cuam tshuam nrog cov kab mob me me, tus kab mob tuag coob tshaj plaws hauv keeb kwm lub luag haujlwm rau kev puas tsuaj tsis sib xws ntawm tib neeg cov neeg nyob rau ntau pua xyoo dhau los. Nrog rau kev tshem tawm tag nrho thiab kev tso tseg tom ntej ntawm kev txhaj tshuaj tiv thaiv kab mob me me (uas tau muab qee qhov kev tiv thaiv kab mob khaub thuas tiv thaiv kab mob npaws ib yam nkaus), cov tib neeg tam sim no tau txo qis ntau ntawm kev tiv thaiv kab mob no. Qhov no piav qhia txog kev nce tam sim no thiab kis tus kab mob liab los ntawm nws cov cheeb tsam nyob hauv Africa.  

Mpox yog tus kab mob kis los ntawm tus kab mob monkeypox. Mpox tuaj yeem kis tau mus rau tib neeg los ntawm kev sib cuag lub cev nrog cov neeg muaj mob, lossis nrog cov khoom tsis huv, lossis nrog cov tsiaj muaj kab mob.  

Cov tshuaj tiv thaiv Mpox tam sim no siv:  

Rau cov neeg laus noj qab nyob zoo, uas tsis yog-replicating (MVA-BN), tsawg replicating (LC 16) los yog replicating tshuaj tiv thaiv raws li cov tshuaj tiv thaiv (ACAM2000) yog tsim nyog.  

MVA-BN yog hom tshuaj tiv thaiv mpox thib 3 uas tau siv los ua ob koob tshuaj subcutaneous txhaj tshuaj tsawg kawg 4 lub lis piam sib nrug. Ob koob tshuaj 1 thiab 2 ntawm MVA-BN muaj txiaj ntsig zoo ntawm kev tiv thaiv mpox. 

LC16 thiab ACAM2000 yog ib koob tshuaj tiv thaiv mpox.  

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References:  

1. WHO Xov Xwm Tshaj Tawm - WHO caw cov tuam txhab tshuaj tiv thaiv mpox xa cov ntaub ntawv rau kev ntsuas kub ntxhov. Published 09 August 2024. Muaj nyob ntawm https://www.who.int/news/item/09-08-2024-who-invites-mpox-vaccine-manufacturers-to-submit-dossiers-for-emergency-evaluations  

2. WHO. Cov tshuaj tiv thaiv kab mob thiab tshuaj tiv thaiv kab mob ntshav liab: Kev taw qhia ib ntus, 16 Kaum Ib Hlis 2022. Muaj nyob ntawm https://iris.who.int/bitstream/handle/10665/364527/WHO-MPX-Immunization-2022.3-eng.pdf  

3. Pischel L., thiab al 2024. Cov tshuaj tiv thaiv zoo ntawm 3rd tiam mpox txhaj tshuaj tiv thaiv mpox thiab kab mob hnyav: Kev tshuaj xyuas thiab kev tshuaj ntsuam xyuas. Tshuaj tiv thaiv. Muaj nyob online 21 Lub Rau Hli 2024. DOI: https://doi.org/10.1016/j.vaccine.2024.06.021  

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Lwm yam khoom  

Virulent Strain of Monkeypox (MPXV) kis los ntawm kev sib deev (20 Plaub Hlis 2024) 

Monkeypox virus (MPXV) variants muab lub npe tshiab (12 Lub Yim Hli 2022) 

Puas yuav Monkeypox mus rau Corona? (23 Lub Rau Hli 2022) 

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