Lub tuam txhab biotech, Moderna, Inc. tau tshaj tawm tias 'mRNA-1273', lawv cov tshuaj tiv thaiv mRNA tiv thaiv tus kabmob tshiab tau pom cov txiaj ntsig zoo hauv theem 1 kev sim tshuaj.
Hauv kev sib tw rau kev txhim kho cov tshuaj tiv thaiv rau kev kho mob ntawm Covid-19, Moderna Inc., tau tshaj tawm rau 18th Tsib Hlis 2020 txog cov txiaj ntsig zoo ntawm lawv mRNA tshuaj tiv thaiv hu ua mRNA-12731. Phase I kawm tau qhia tias mRNA-1273 tshuaj tiv thaiv mRNA-1273 ua rau lub cev tiv thaiv kab mob ua rau muaj kev cuam tshuam cov tshuaj tiv thaiv kab mob hauv txhua yim yim tus neeg koom nrog thoob plaws 25 µg thiab 100 µg koob tshuaj. Qhov nruab nrab cov tshuaj tiv thaiv kab mob titers tau mus txog qib tib yam li pom hauv cov neeg mob uas tau zoo los ntawm tus kab mob COVID-19.
tshuaj tiv thaiv mRNA-1273 feem ntau muaj kev nyab xeeb thiab zam tau zoo. Cov ntaub ntawv kev nyab xeeb tau ua raws li qhov tau pom hauv kev tshawb fawb Moderna ua ntej tau ua nrog cov tshuaj tiv thaiv kab mob sib kis.
Preclinical kev tshawb fawb ntawm nas txhaj tshuaj tiv thaiv nrog mRNA-1273, tom qab lawv tau sib tw nrog SARS-CoV-2 tus kab mob no pom tias mRNA-1273 tiv thaiv kab mob sib kis thiab ua rau muaj kev tsim cov tshuaj tiv thaiv kab mob nruab nrab nrog cov titre zoo ib yam li cov neeg mob uas tau koom nrog hauv Phase I kawm.
Cov txiaj ntsig tau txhawb nqa tau los ntawm Kev Kawm Phaj 1 yuav pab pib qhov kev sim ntxiv sai sai, nrog Phase 3 xav tias yuav pib thaum Lub Xya Hli 2020, tseem tos qhov kawg ntawm cov txheej txheem kho mob thiab yog tias txhua yam mus zoo, cov tshuaj tiv thaiv yuav pom lub teeb ntawm lub hnub, npaj rau yuav muab tshuaj rau cov neeg mob sai dua li qhov xav tau, txij li FDA tau muab Fast Track designation2 rau qhov project.
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Qhov chaw:
1. Moderna, Inc. 2020. Xovxwm tshaj tawm - Moderna tshaj tawm Cov ntaub ntawv zoo ib ntus ntu 1 rau nws mRNA Tshuaj tiv thaiv (mRNA-1273) Sib Dab Neeg Coronavirus. Tshaj tawm rau lub Ob Hlis 18, 2020. Muaj nyob online ntawm https://investors.modernatx.com/news-releases/news-release-details/moderna-announces-positive-interim-phase-1-data-its-mrna-vaccine
2. Moderna, Inc. 2020. Xovxwm Tshaj Tawm - Moderna Tau txais FDA Fast Track Designation for mRNA Vaccine (mRNA-1273) Against Novel Coronavirus. Tshaj tawm rau lub Ob Hlis 12, 2020. Muaj nyob online ntawm https://investors.modernatx.com/news-releases/news-release-details/moderna-receives-fda-fast-track-designation-mrna-vaccine-mrna
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