Tau muaj qhov nce sai hauv qhov sib txawv ntawm SARS CoV-2 hauv Fabkis thaum Lub Rau Hli 2021 raws li kev tshuaj xyuas ntawm 5061 cov qauv zoo.1. Ob peb lub lis piam tom ntej no yog qhov tseem ceeb heev nrog rau qhov tshwm sim ntawm nthwv dej thib peb vim tias muaj kev sib kis ntau dua ntawm delta variant thiab qhov cuam tshuam nws yuav muaj rau pej xeem thiab ntiag tug kev noj qab haus huv. Kev tuag thiab kev mob tshwm sim los cuam tshuam nrog nthwv dej thib peb yuav nyob ntawm qhov ua tau zoo ntawm AstraZeneca ChAdOx1 koob tshuaj tiv thaiv, mus rau delta variant, uas tau muab rau cov pej xeem.
Kev soj ntsuam ntawm UK cov pej xeem uas tau txais thawj zaug thiab thib ob koob tshuaj ChAdOx 1 tshuaj tiv thaiv qhia tias tom qab thawj koob tshuaj, cov tshuaj tiv thaiv tsis zoo (33.5% tawm tsam B.1.617.2 [delta variant] piv rau 51.1% tawm tsam B.1.1.7 variant)2. Tsis tas li ntawd, tom qab koob thib ob kuj, cov tshuaj tiv thaiv tsis zoo (59.8% tawm tsam B.1.617.2 [delta variant] piv rau 66.1% tawm tsam B.1.1.7 variant)2.
Vim li cas peb thiaj pom cov nthwv dej sib txawv Covid-19 nyob rau hauv ntau lub teb chaws ntawm txawv lub sij hawm? Cov lus teb yuav dag nyob rau hauv qhov tseeb tias kev tiv thaiv pab tsiaj tseem tsis tau txog thiab "muab xauv" tau raug tshem tawm ua rau nthwv dej tom ntej ntawm COVID-19. Qhov "lock-down" qhov tseeb tiv thaiv kev kis tus kab mob thiab yog li tiv thaiv kab mob sib kis thiab hloov pauv. Txawm li cas los xij, qhov kev sib tw tau ntsib yog qhov tseeb tias txhua lub sijhawm nthwv dej tuaj, tus kab mob tau txais txoj hauv kev hloov pauv uas yuav ua rau muaj kev sib kis ntau dua (daim ntawv ntawm tus kab mob uas muaj kev sib kis ntau dua uas ua rau muaj sia nyob ntawm txoj kev xav zoo tshaj plaws), yog li negating cov nyhuv ntawm tshuaj tiv thaiv pab mus txog qhov sib txawv ntawm tus kab mob yav dhau los. Tsis ntev los no, ib qho kev hloov tshiab hu ua delta plus variant tau tshwm sim uas sib txuas cov delta variant nrog K417N kev hloov pauv (thawj pom hauv Beta variant uas tshwm sim hauv South Africa). Qhov no delta plus variant yog resistant rau antibody therapy kho. Tag nrho cov no ua rau muaj kev nyuaj nyuaj nyob rau hauv cov nqe lus ntawm kev tiv thaiv tsiaj txhu.
Pab tiv thaiv kab mob3 tseem tuaj yeem mus txog yog tias cov tshuaj tiv thaiv tau muab kev tiv thaiv tseem ceeb tsawg dua 90% raws li tau thov los ntawm mRNA cov tshuaj tiv thaiv ntawm Pfizer thiab Moderna (93.4% nrog 2 koob tshuaj Pfizer tawm tsam B.1.1.7 variant thiab 87.9% tawm tsam B.1.617.2 [delta variant]). Txawm li cas los xij, cov tshuaj tiv thaiv no tau siv dav hauv Asmeskas thiab UK, thaum lwm lub tebchaws feem ntau yog nyob ntawm ChAdOx1 (AstraZeneca) tshuaj tiv thaiv, tshuaj tiv thaiv Lavxias Sputnik V thiab tshuaj tiv thaiv Indian Covaxin. Cov tshuaj tiv thaiv no tuaj yeem lossis tsis tuaj yeem muab kev tiv thaiv zoo tiv thaiv cov qauv tsim tawm tshiab. Thaum tsis muaj cov tshuaj tiv thaiv zoo thiab qhov tseeb tias cov kab mob kis tau zoo tshiab tau tsim yuav luag txhua lub sijhawm tus kab mob rov ua dua ua rau muaj kev hloov pauv, nws yuav siv sijhawm li ob peb lub hlis txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau tiv thaiv tsiaj txhu thiab cov nthwv dej tom ntej ntawm COVID-19 yuav txuas ntxiv mus txog qhov muaj txiaj ntsig zoo. kev tiv thaiv tau tiav.
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References
- Alizon S., Haim-Boukobza S., et al 2021. Rapid spread of the SARS-CoV-2 δ variant in the area of Paris (France) in June 2021. Posted June 20, 2021 in Preprint medRxiv. DOI: https://doi.org/10.1101/2021.06.16.21259052
- Bernal JL, Andrews N, Gower C et al. Kev ua tau zoo ntawm cov tshuaj tiv thaiv COVID-19 tawm tsam B.1.617.2 variant. Tshaj tawm Lub Tsib Hlis 24, 2021. DOI: https://doi.org/10.1101/2021.05.22.21257658
- Soni R 2021. COVID-19: Kev Ntsuam Xyuas Kev Tiv Thaiv Kab Mob thiab Tiv Thaiv Kab Mob. Muaj nyob online ntawm https://www.scientificeuropean.co.uk/covid-19/covid-19-an-evaluation-of-herd-immunity-and-vaccine-protection/
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